화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2012년 가을 (10/31 ~ 11/02, 대전컨벤션센터)
권호 16권 2호
발표분야 포스터-생물공학
제목 Enhanced antioxidant and anticancer activity of microalgae mutants
초록 To improve industrial strain of microalgae Arthrospira platensis (A. platensis), electron beam irradiation was performed. A. platensis cells were exposed to low energy (0.18 MeV, 0.3 mA) and high energy (0.2 MeV, 1.2 mA). Although the cell growth was decreased by high energy electron beam, lipid accumulation was exceedingly increased. In this study, mutants of A. platensis by high energy electron beam, EM240 and EM384, were isolated and characterized. After screening, mutants EM240 and EM384 having higher growth rate, cellular lipid content and phycocyanin pigment than parental strain were isolated. The increased active compounds of mutants, such as phycocyanin and lipids, revealed antioxidant and anticancer activities. It is the first reports on characterization of mutant strains of microalgae by electron beam irradiation. Microalgae species with improved growth rate and enhanced active compounds make the commercial process more feasible in industry.  
저자 김영화, 박현진, 이재화
소속 신라대
키워드 microalgae; electron beam; mutants; antioxidant; anticancer
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