| 학회 |
한국고분자학회 |
| 학술대회 |
2014년 봄 (04/10 ~ 04/11, 대전 컨벤션센터) |
| 권호 |
39권 1호 |
| 발표분야 |
의료용 고분자 부문위원회(초청-영어발표/포스터-국문발표 가능) |
| 제목 |
Gold nanoparticle-based SERS probes for cancer diagnosis and therapy |
| 초록 |
Highly sensitive optical imaging technology using metal nanoparticles has been extensively applied to cellular imaging and biomedical diagnostics. Surface-enhanced Raman scattering (SERS) as the inelastic light scattering of gold or silver nanoparticles is emerging as a powerful alternative for identifying specific biological targets in live cells. In this study, we synthesized a novel gold nanoparticle-based SERS probes. Photosensitizer (PS) was introduced to the gold nanoparticle-based SERS probes as a Raman reporter for cancer diagnosis and therapy. The optical property and morphology of HA-based gold nanochains were investigated. In vitro tests using HeLa cells indicated that the gold nanoparticle-based SERS probes exhibited excellent cellular localization and killed HeLa cells effectively compare to free PS under laser radiation. |
| 저자 |
자오린린, 김소연
|
| 소속 |
충남대 |
| 키워드 |
gold nanoparticle; SERS
|
| E-Mail |
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