화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2009년 가을 (10/15 ~ 10/16, 서울산업대학교 내 서울테크노파크)
권호 13권 2호
발표분야 고분자(포스터)
제목 Synthesis and evaluation of injectable chondroitin sulfate-poly(ethylene oxide) hydrogel
초록 Hydrogel refers to a three dimensional polymeric network that is cross-linked via various chemical and/or physical bonds and able hold a large amount of water in the wet state. Several methods of gel fabrications have been developed such as UV-polymerization, introducing non-reversible covalent bonds, self-assembly, stimulus-dependent gel formation. Among thesemethods, in situ hydrogels are of most interest. We synthesized injectable chondroitin sulfate-poly(ethylene)oxide hydrogel via Michael type addition reaction. We confirmed derivatization of chondroitin sulfate for hydrogel formation by FTIR, NMR and XPS.In vitro cell behaviors were later evaluated by seeding bone cells on the surface and encapsulation of the hydrogel for its application in tissue engineering.
저자 조성연, 김도연, 우정훈, 조선영, 김수미, 노인섭
소속 서울산업대
키워드 chondroitin sulfate; hydrogel; injectable
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