화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2009년 봄 (04/15 ~ 04/17, 호텔인터불고(대구))
권호 13권 1호
발표분야 콜로이드계면화학
제목 In vitro skin permeation of Triclosan loaded in cubosome
초록 Cubosomes containing triclosan (TS) were prepared by dispersing the mixture film of monoolein (MO)/TS in distilled water. Pluronic F127 was used as the dispersing agent. In vitro skin permeation of TS loaded in the cubosomes was investigated using a diffusion cell drive. In order to increase the solubility of TS, hydroxypropyl-α-cyclodextrin was dissolved in the receptor solution. As a control, TS dissolved in ethanol or propylene glycol was used. In addition, the physical characteristics such as thermo stability, size distribution, and apparent shape were investigated using the techniques of differential scanning calorimetry, dynamic light scattering and transmission electron microscopy.
저자 권택관, 강미경, YANG XIA, 홍연지, 김진철
소속 강원대
키워드 skin permeation; Triclosan; cubosome
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