| 초록 |
After recognition of 3D bioprinting as a critical issue in tissue engineering and regenerative medicine society, many hydrogels have been developed by using polymeric biomaterials. Even though some gels have shown good performances in 3D bioprinting, still their performances do not meet the requirements enough to be used. In this study, a hydrogel consisting of two biocompatible biomaterials, deacetylated hyaluronic acid-tyramine (deHATA) and gelatin-hydroxy propionic acid (GH) has been evaluated for its possibility as a bioink. Hydrogel synthesis was obtained by EDC/NHS conjugation method. Properties of the hydrogels have been evaluated such as gelation time (0~5 minutes), rheology (250~4000 Pa), cytocompatibility, biodegradability. Printing of hydrogel with cell loaded in lattice forms were evaluated by using 3D bioprinting system. (6 layers) Acknowledgement: NRF-2018R1A2B2004529 |
