| 초록 |
Tryptophan is an aromatic acid and well known as a fluorescence quencher with PET mechanism. This fluorescence quenching ability changes by the distance of two residue, and can be figured out by the peptide chain. Herein, we developed a series of fluorescence sensors based on NBD as a fluorophore and tryptophan as a receptor connected through different length of glycine chains. This series of fluorescence sensors can detect copper and mercury ions by turn on or turn off response depending on length of glycine amino acids between the NBD and the tryptophan residue. While fluorescence of sensors changes, they make complex structures with metal ions. This complex size is measured by DLS and SEM with showing differences by length of a glycine linker. |
