화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2012년 가을 (10/24 ~ 10/26, 부산 BEXCO)
권호 18권 2호, p.1922
발표분야 생물화공
제목 Optimized Immobilization of Formate Dehydrogenase to Catalyze the Reduction of Carbon Dioxide
초록 The global warming is one of the most important worldwide issues since the temperature of the earth has increased. There are some ways to decrease the carbon dioxide concentration in the atmosphere. NAD-dependent formate dehydrogenase (FDH) which has been widely utilized for enzymatic NADH regeneration could be used as the first enzyme of cascade reaction for the synthesis of methanol from carbon dioxide. Among the cascade reaction from CO2 to methanol, the first step, reduction of carbon dioxide, is the rate limiting step since the activation energy of this step is the highest. TsFDH is reported to show much higher carbon dioxide reduction activity than commercially available Candida boidinii FDH. In this study we reported several immobilization techniques for TsFDH including CLEA(Cross-linked enzyme aggregate) and physical adsorption and biosilicification to apply continuous production of formate from CO2.
저자 최현준, 이민철, 박정우, 백성원, 이지흔, 주정찬, 김용환
소속 광운대
키워드 Immobilization; Formate dehydrogenase; CLEA; Biosilicification
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