화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2019년 봄 (04/10 ~ 04/12, 부산컨벤션센터(BEXCO))
권호 44권 1호
발표분야 기능성 고분자
제목 Microfluidic system for easy monitoring of drug delivery and cytotoxicity
초록 Micro-fluidic system can be used in drug release study for monitoring of the drug concentration in micro-level, may provide more precise information about the efficacy of the drug. Here, we fabricated a micro-fluidic device for the study of an anticancer drug efficiency and toxicity with the drug-encapsulated hydrogel beads placed within a micro-channel of the device. We utilized layer-by-layer deposition method to modify the surface of the micro-channel of the device in order to prevent bio-fouling as well as provide the better cell culturing condition. The results of this study indicate that the microchannels suitably surface functionalized might be a available to effectively monitor cancerous cells upon the exposure to a anti-cancer drug encapsulated in micro-beads.
저자 김다름, 이수진, 양성윤
소속 충남대
키워드 microfuidic; cytotoxicity; drug release; anti cancer; layer-by-layer deposition
E-Mail