| 학회 |
한국화학공학회 |
| 학술대회 |
2015년 봄 (04/22 ~ 04/24, 제주 ICC) |
| 권호 |
21권 1호, p.40 |
| 발표분야 |
고분자 |
| 제목 |
Poly(N-isopropyl acrylamide-co-Acrylic acid)-graft-Polyaspartate coated Magnetic Nanoparticles for Molecular Imaging and Therapy |
| 초록 |
A series of pH- and thermo-sensitive poly(N-isopropyl acrylamide-co-acrylic acid) were synthesized by radical polymerization and grafted on polysuccinimide backbones. The polysuccinimide derivatives synthesized were coated on iron oxide magnetic nanoparticles to make core-shell structure for potential applications in drug delivery systems with molecular imaging and therapy. The structure of polymer-shell was confirmed by FT-IR, 1H-NMR spectroscopies . Its thermal behaviors was tested by UV-Vis spectroscopy. The particle size and its distribution was measured by dynamic light scattering (DLS) and transmission electron microscope (TEM). The mean diameter of the core-shell structure is from 20 to 80 nm. |
| 저자 |
TRAN THI THUY VAN, 김덕준
|
| 소속 |
성균관대 |
| 키워드 |
iron oxide; nanoparticles; polysuccinimide; PNIPAM
|
| E-Mail |
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| 원문파일 |
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