| 초록 |
One of the most challenging issues facing medical and dental industries today is forming and maintaining strong adhesion on polar surface in the presence of moisture. However, most commercially available adhesives cannot be applied on those wet surfaces. On the other hand, marine mussels have effective adhesion strategies for wet substrates. DOPA is known to play a key role in the mussel underwater adhesion by forming underwater adhesive bonding with a variety of molecules. But recent nanomechanical studies on mussel adhesive proteins suggest another key underwater adhesion mechanism, cation-π interaction. Cation-π interaction, was suggested as a main contributor to the cohesive nature of mfp-1. In this study, cation-π interaction in DOPA deficient mussel adhesive protein (Rmfp-1) was measured using the SFA experiments and computer simulation. |
