화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2016년 가을 (10/19 ~ 10/21, 대전컨벤션센터)
권호 22권 2호, p.2567
발표분야 바이오메디컬 소재 및 응용 한·일 국제 심포지엄(특별 심포지엄)
제목 Ion-responsive star copolymers and their biomedical applications
초록 Star shaped block copolymers were newly synthesized using ATRP (atrom transfer radical  polymerization) technique. The copolymer has a hydrophobic core composed of dendritic polyester (DPE) and hydrophilic graft chains composed of block copolymer of oligo (ethylene glycol) methyl ether acrylate (OEGA) and acrylic acid (AA). Due to the ionic interaction between AA and calcium ions, the star copolymer formed hydrogel rapidly by mixing the copolymer and calcium ions. Then, its gelation mechanism was investigated using fluorescence resonance energy (FRET). Finally its biocompatibility was investigated in vitro and in vivo.
저자 Taichi Ito
소속 The Univ. of Tokyo
키워드 Hydrogel; star copolymer; ATRP; ionically crosslinked
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