| 학회 |
한국화학공학회 |
| 학술대회 |
2016년 가을 (10/19 ~ 10/21, 대전컨벤션센터) |
| 권호 |
22권 2호, p.1802 |
| 발표분야 |
생물화공 |
| 제목 |
Highly Porous Regenerated Bacterial Cellulose Scaffolds for in vitro Tissue Regeneration |
| 초록 |
This study reports the fabrication of highly porous regenerated bacterial cellulose (rBC) scaffolds through solution casting and porogen leaching method. The scaffolds fabrication was carried out through dissolution of BC in N-methylmorpholine N-oxide (NMMO) followed by subsequent addition of NaCl microcrystals as porogens. The mixture was quickly casted into molds followed by hardening and solvent and porogen leaching in a water bath at ambient temperature. Field Emission Scanning Electron Microscopy (FE-SEM) confirmed the microporous nature of the scaffolds. Animal fibroblast cells adhered and proliferated well on the rBC scaffolds while cell toxicity assay confirmed their nontoxic nature. Alkaline phosphatase (ALP) activity and Alizarin red staining (ARS) revealed osteogenic differentiation of animal osteoblasts on the scaffolds. These results demonstrate our rBC scaffolds as potential candidate for future tissue regeneration applications. |
| 저자 |
Shaukat Khan1, Mazhar Ul-Islam1, Muhammad Israr2, 김예지3, 장재현1, 노태용1, 박중곤1
|
| 소속 |
1경북대, 2College of Engineering, 3Dhofar Univ. |
| 키워드 |
동식물세포/조직공학 |
| E-Mail |
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| VOD |
VOD 보기 |
| 원문파일 |
초록 보기 |
