| 초록 |
Phototherapy, such as photothermal therapy (PTT) and photodynamic therapy (PDT) has outstanding potential in cancer treatment due to their tremendous therapeutic effects otherwise minimizing normal tissue damages. In this context, titanium dioxide (TiO2)-based materials, extensively investigated as photocatalysts due to their high-efficiency, cost effectiveness, non-toxicity, and photostability, have been suggested for reactive oxygen species (ROS) generator. However the wide band gap of TiO2 (3.2 eV) has remained a barrier in in vivo phototherapy because only NIR laser penetrate the tisue. In this work we propose a sidestep in the intrinsic limitation of conventional TiO2 by exploring the surface plasmon resonance (SPR) effect of rationally designed anatase TiO2-coated gold nanobipyramids. it has great potential for phototherapy. |
