화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2010년 가을 (10/07 ~ 10/08, 대구 EXCO)
권호 35권 2호
발표분야 의료용 고분자
제목 Preparation and characterization of Pullulan-g-Poly(ε-caprolactone) for drug delivery system
초록 To developed Pullulan based Anticancer agent carrier, Pullulan were chemically modified with hydrophobic group of Poly(ε-caprolactone). The physicochemical properties of the Pullulan-g-Poly(ε-caprolactone) (PULPCL) copolymer were investigated by using 1H-NMR, dynamic light scattering, TEM and spectrofluorophotometer. PULPCL nanoparticles were prepared by dialysis method. Anticancer agent-loaded PULPCL (PULPCL-Aa) nanoparticles were investigated by 1H-NMR, dynamic light scattering measurement. The PULPCL-Aa was investigated to pharmacentcal application as a Anticancer agent carrier.
저자 박준규, 홍락준, 이경재, 김원석, 최창용, 나상권, 장미경, 나재운
소속 순천대
키워드 Pullulan; Poly(ε-caprolactone); nanoparticles; drug delivery system
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