| 초록 |
Lanthanide-doped upconversion nanoparticles (UCNPs), which can emit high energy visible light upon near-infrared (NIR) excitation, have been intensively employed for biomedical field due to high photostability, deep penetration into tissues, low toxicity, and significantly improved signal-to-noise ratio in optical bioimaging. In general, since green emissions emitted from UCNP is greater than red emissions, photodynamic therapy (PDT) using photosensitizer (PS) activated for red emissions has little effect. In this study, a multi-shell structured UCNPs, which have enhanced photoluminescence and can emit UV, blue, green and red emission, were fabricated. Then, their surface modification was conducted for NIR-triggered PDT and bioimaging. In addition, the morphology and photoluminescence effect of multi-shell structured UCNPs were investigated. |
