| 학회 |
한국재료학회 |
| 학술대회 |
2009년 가을 (11/05 ~ 11/06, 포항공과대학교) |
| 권호 |
15권 2호 |
| 발표분야 |
D. Health and Biological Materials(생체 및 의용재료) |
| 제목 |
Fabrication of gelatin-amorphous CaP nano fibrous mat for using as fast bone healing material |
| 초록 |
Using the favorable resorption behavior of amorphous Calcium phosphate (CaP) we fabricated a gelatin based nano fibrous mat by electrospinning for using as a fast healing patch for minor bone defects. Bone is predominantly formed by an inorganic phase of nano-crystalline HAp materials and nano fibrous protein material of collagen. The osteoblast cells, which are the bone formation cells and are key to the new bone formation, receive these materials to form new bone. Taking these considerations we make a new nano fibrous mat of amorphous CaP and gelatin, which is derived from collagen itself. A polymer carrier of poly caprolactone (PCL) was used in the system to stabilize the materials in biological condition. The electrospinning conditions were optimized for smooth mat without any droplet formation. The fabricated mat was characterized for its morphology by SEM. Mechanical properties like tensile strength was evaluated. To investigate the bio-compatibility we performed the MTT assay and investigated its resorption behavior and apatite formation behavior by SBF immersion. |
| 저자 |
Swapan Kumar Sarkar, Ho Yeon Song, Byong Taek Lee
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| 소속 |
Soonchunhyang Univ. |
| 키워드 |
Amorphous calcium phosphate; electrospinning; gelatin; bone healing
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| E-Mail |
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