| 초록 |
Efforts have long been directed to develop tissue substitutes appropriate for the treatment of damaged human tissues. Maintaining skin tissues under healthy conditions has been one of critical factors in cosmetic industries. Skin tissue is strongly affected by various factors, such as ageing, sun ultraviolet, chemicals, and environmental pollution. For soft tissue substitutes, there are many requirements, including biocompatibility, biodegradability, and capability to promote tissue regeneration. In this study, we used hyaluronic acid for the preparation of hydrogel as skin tissue substitutes. In addition to examination on physical properties of hyaluronic acid gel, interactions with fibroblast were characterized at gene, protein, and cell levels. |
