| 학회 |
한국공업화학회 |
| 학술대회 |
2008년 가을 (11/12 ~ 11/14, ICC 제주) |
| 권호 |
12권 2호 |
| 발표분야 |
고분자 |
| 제목 |
Microstructure and mechanical properties of PCL-BCP-HPMC hybrid bone graft substitutes and an evaluation of their biocompatibility |
| 초록 |
Hybrid scaffolds have been fabricated by salt-leaching and freeze-drying methods using polycaprolactone (PCL), biphasic calcium phosphate (BCP) and hydroxypropyl methylcellulose (HPMC). The obtained organic/inorganic hybrid scaffold showed interconnected and open pores, and a quadrilateral shaped pore of about 200 to 500 μm in diameter. In particular, the microstructures and phase of the porous scaffolds were investigated using the XRD, FT-IR/ATR and SEM techniques. For an evaluation of the biocompatibilities of the porous scaffolds, indirect cytotoxicity measurement of the scaffolds with human fibroblast indicated that the materials were non-toxic. |
| 저자 |
윤민호, 한설희, 권성진, 안성준, 임윤묵, 노영창
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| 소속 |
한국원자력(연) |
| 키워드 |
polycaprolactone; biphasic calcium phosphate; hydroxypropyl methylcellulose; scaffold; bone graft substitute
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| E-Mail |
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