화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2007년 가을 (11/02 ~ 11/03, 한경대학교)
권호 11권 2호
발표분야 생물공학
제목 Effect of 1α,25-dihydroxyvitamin D3 immobilized within onto calcium phosphate on the marker gene expression of osteoblastic MG63 cell
초록 1α,25-dihydroxyvitamin D3 has been reported to affect the differentiation of osteoblast. Calcium phosphate is well-known to have biological compatibility. We attempt to improve the osteointegration by mobilizing 1α,25-dihydroxyvitamin D3 within calcium phosphate. The expression levels of marker gene such as osteocalcin, osteopontin, osteonectin, alkaline phosphatase, TGF-β, and typeⅠ-collagen has been analyzed using PCR. According to the experimental results, the gene expression level varies in response to the presence of 1α,25-dihydroxyvitamin D3 within calcium phosphate.
저자 홍윤정, 정재영, 이우걸
소속 단국대
키워드 PCR; ; 25-dihydroxyvitamin D3; calcium phosphate
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