초록 |
Collagen membranes have been widely applied to wound healing, cell regeneration, etc due to its biocompatibility and physicochemical properties in the field of tissue engineering. A scaffold material should have space where cells can grow and keep water to provide nutrient to the cells. In this study, we fabricated porous collagen membranes using directional freezing of collagen suspension. The pore size was about 80 um. The through-thickness pores formed by this method contributed to directional cell growing. Reduced graphene oxide (rGO) strengthened molecular interaction was dispersed in collagen suspension. We confirmed that the collagen-rGO membrane had higher elasticity than the normal control collagen membrane. We expect that conductivity of rGO helps cell growing based on the fact that cell activity can be actively generated under an electrical stimulus. |