| 학회 | 한국화학공학회 |
| 학술대회 | 2013년 가을 (10/23 ~ 10/25, 대구 EXCO) |
| 권호 | 19권 2호, p.1564 |
| 발표분야 | 생물화공 |
| 제목 | 피부침투 활성성분 운반을 위한 아젤라이산 베시클 운반체 |
| 초록 | Azelaic acid (1,7-heptanedicarboxyilic acid, AZA) is a naturally occurring non-toxic straight chain, saturated dicarboxylic acid derived from Pityrosporum ovale, the organism responsible for pityriasis versicolor. Azelaic acid appears to selectively influence the mechanism of hyperactive and abnormal melanocytes, but minimally influences normal skin pigmentation, freckles, nevi and senile lentigenes. he compound is also able to bind amino and carboxyl groups and may prevent the interaction of tyrosine in the active site of tyrosinase and thus function as a competitive and reversible inhibitor. Its lightening effect appears to be selective and most apparent in highly active melanocytes, with minimal effects in normally pigmented skin. This review describes the barrier properties of the skin, how active ingredients penetrate the skin by vesicle technique that has been used to enhance active ingredient penetration across skin. |
| 저자 | 김명훈1, 김선남2, 김광수3 |
| 소속 | 1캠브리지대, 2나드리화장품㈜ 기술(연), 3(주)에이티랩 기술(연) |
| 키워드 | |
| 원문파일 | 초록 보기 |
