| 학회 |
한국고분자학회 |
| 학술대회 |
2007년 봄 (04/12 ~ 04/13, 제주 ICC) |
| 권호 |
32권 1호 |
| 발표분야 |
나노바이오기술용 고분자(의료용 고분자 부문위원회) |
| 제목 |
Controlled Cellular Interaction Using H-bonded Biodegradable Polyelectrolyte Multilayers |
| 초록 |
Layer-by-Layer deposition (LbL) is a versatile technique whereby ultrathin films are assembled from the repetitive, sequential adsorption of oppositely charged polyelectrolytes from dilute aqueous solution. In previous study, polyacrylamide (PAAm) containing hydrogen-bonding driven multilayer films were stabilized and revealed an excellent bio-inert effect. The multilayers of PAAm with weak polyelectrolytes, such as poly(acrylic acid)(PAA) or poly(aspartic acid)(PASA) were investigated for their surface-cell interaction using 293 epithelial cells. H-bonded PAA and biodegradable PASA surfaces were determined as cell adhesion controllable surfaces. Micro-patterning of the cell-interactive polyelectrolytes was applied onto the H-bonded multilayer films. Cell-adhesive polypeptide linker was used to study specific cellular interactions onto tje film. Nanoparticle hybrid systems were also studied. |
| 저자 |
서주용, 양성윤
|
| 소속 |
충남대 |
| 키워드 |
Polyelectrolyte multilayers; H-bond; cell interaction
|
| E-Mail |
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