| 학회 |
한국공업화학회 |
| 학술대회 |
2007년 가을 (11/02 ~ 11/03, 한경대학교) |
| 권호 |
11권 2호 |
| 발표분야 |
정밀화학 |
| 제목 |
A noble synthesis of 3, 3-difluoro-2-pyrrolidones |
| 초록 |
Synthesis of 3, 3-difluoro-2-pyrrolidones (7) were accomplished by the reaction of ethyl 2,2-difluoro-4-iodo-4-(trimethylsilyl) butanolate (4) with primary amines followed by desilylation. The key intermediate (4) was prepared from the addition reaction of trimethylvinylsilane (3) to ethyl difluoroiodoacetate (2) in the presence of Cu(0). Ethyl difluoroiodoacetate (2) was prepared starting from ethyl bromodifluoroacetate(1) via Reformatsky-type reaction. |
| 저자 |
송미선1, 류성렬2, 곽경철1, 김기선2, 채규윤1
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| 소속 |
1원광대, 2대불대 |
| 키워드 |
3; 3-difluoro-2-pyrrolidone; ethyl 2; 2-difluoro-4-iodo-4-(trimethylsilyl) butanolate; Ethyl difluoroiodoacetate
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| E-Mail |
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