| 학회 |
한국고분자학회 |
| 학술대회 |
2008년 봄 (04/10 ~ 04/11, 컨벤션 뷰로(대전)) |
| 권호 |
33권 1호 |
| 발표분야 |
의료용 고분자 |
| 제목 |
Characterization of PLGA/Demineralized Bone Particle Composites as Scaffolds |
| 초록 |
We developed that composites scaffolds by combining PLGA and DBP. PLGA scaffolds were prepared by solvent casting/salt leaching method and were immersed in DBP acidic solution under a vacuum so that the scaffold pores filled with DBP solution. The structure morphology of scaffolds was observed by SEM. We performed FTIR to confirm whether DBP solution impregnated into PLGA scaffolds. Water absorption ability was determined by measuring the weight of scaffolds for 12 days. We confirmed that DBP solution was impregnated into the pores of PLGA scaffold. The ability to absorb water was increased in PLGA/DBP scaffold than in PLGA scaffold. This result suggested that high water absorption ability of PLGA/DBP scaffold would help interaction with cells seeded in scaffolds. A novel scaffold was manufactured to ensure the possibility of application of degenerated IVD. This work was supported by SCRC (SC3100) from KMOST. |
| 저자 |
홍현혜1, 백미옥1, 김순희1, 소정원1, 임지예1, 정수현1, 이해방2, 강길선1
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| 소속 |
1전북대, 2한국화학(연) |
| 키워드 |
PLGA; DBP
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| E-Mail |
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