| 학회 |
한국고분자학회 |
| 학술대회 |
2008년 봄 (04/10 ~ 04/11, 컨벤션 뷰로(대전)) |
| 권호 |
33권 1호 |
| 발표분야 |
의료용 고분자 |
| 제목 |
Characterization of Keratin/PLGA Scaffold |
| 초록 |
Keratin is the major structural fibrous protein providing outer covering. Keratin is useful as natural biomaterial. We developed the keratin loaded poly(L-lactide-co-glycolide)(PLGA) scaffolds for tissue engineering. We developed the keratin loaded poly(L-lactide-co-glycolide)(PLGA) scaffolds. 0, 10, 20 and 50 wt% of keratin scaffolds were prepared by solvent casting/salt leaching method. We characterized porosity, wettability, and water uptake ability. We isolated Bone marrow mesenchymal stem cells (BMSCs) from female Fischer rat , we seeded BMSCs into the inner core of the hybrid scaffold. Celluar viability were assayed by MTT test. We confirmed Characterization Keratin/PLGA scaffold. In MTT assay results, cell viability in scaffolds impregnated 10 and 20 wt% of keratin were higher than other scaffolds. We confirmed that Keratin/PLGA scaffold is hydrophilicby wettability, and water uptake ability measurement results. Acknowledgements This research was supported by SCRC(SC3100). |
| 저자 |
오아영1, 김순희1, 김수미1, 김근아1, 이해방2, 이종문1, 강길선1
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| 소속 |
1전북대, 2한국화학(연) |
| 키워드 |
keratin |
| E-Mail |
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