화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2010년 가을 (10/07 ~ 10/08, 대구 EXCO)
권호 35권 2호
발표분야 의료용 고분자
제목 Preparation of Liposome Carriers with Various Pressure using SPG Membrane
초록 Liposomes are usually used various particles sizes with various applications. In this study, we prepared various size liposomes using shirasu porous glass (SPG) emulsification. Liposomes were prepared by the thin film cast-hydration method and were permeated through SPG membrane with decreasing membrane pore sizes of 10, 5, 2, 1, 0.7, 0.5 and 0.2 ㎛. The inner structures and sizes of liposomes were confirmed by optical microscopy, cryo-TEM and DLS. The time it took liposomes to pass through the SPG membrane was measured at varying pressure, and liposome size was measured with SPG membrane pass number to confirm correlation of SPG membrane and lipid layer.
저자 황태원1, 박태준1, 이정민1, 고원건1, 정인우2, 김중현1
소속 1연세대, 2경북대
키워드 liposomes; SPG membrane; pressure
E-Mail