| 초록 |
We first successfully produced multilayered nanoemulsion films by using the layer-by-layer deposition of negatively charged nanoemulsion and positively charged polyelectrolytes. The nanoemulsion used in our study was fabricated through assembly of amphiphilic block copolymer and lecithin at the oil-water interface. Basically, the thickness of the nanoemulsion films was tunable to few micrometer scales by solely changing the number of alternate emulsions and polyelectrolytes layers. We figured out that the emulsion films had the thermally responsive heterogeneous phase separation, which is typically referred to as Spinodal decomposition. Taking advantage of this intriguing phase separation behavior, we were able to regulate film wettability and drug release. This result highlighted that many more new applications could be explored for the controlled drug delivery from patch-type soft emulsion film cargos. |
