| 초록 |
Flow lithography (FL), combining photolithography with microfluidic operations, has been a promising technique that can synthesize microparticles having complex morphologies and multi-layered chemical patterns. This technique enables the incorporation of a broad range of functionalities into particles for biological applications such as diagnostics, drug delivery, and tissue engineering. Herein, we investigate that reactive carbon double bonds remain in the polymer networks of the particles synthesized via flow lithography, verify that they could be pernicious to the biological systems and biochemically unstable, and present a straightforward method to eliminate them by the use of click chemistry. We envision that our method can provide a powerful way to prepare inert particles for various biomedical applications such as drug delivery systems and tissue engineering. |
