| 학회 |
한국재료학회 |
| 학술대회 |
2016년 가을 (11/16 ~ 11/18, 경주 현대호텔) |
| 권호 |
22권 2호 |
| 발표분야 |
B. 나노화학/바이오 재료 분과 |
| 제목 |
Active vs Passive Targeting: Preparation and Cellular Uptake of Nanoparticles with Folic Acid and/or Charges |
| 초록 |
We investigated effect of passive and active ligands in cellular uptake. First, both hydroxyl termini of PEO-b-PPO-b-PEO were converted to folic acid(FA; ligand) and trimethylammonium bromide(AB; charge). Then micelle core of FA and AB polymer blends was stabilized by semi-interpenetrating network formation in the presence of fluorescent probe, Nile Red. Lastly, cellular uptake of nanoparticles varying charge and ligand was studied in HeLa by fluorescence microscopy and flow cytometry. |
| 저자 |
Haejoo Kim1, Jun-O Jin2, Seong-Jin Kim3, Peter C.W. Lee4, Minseok Kwak5
|
| 소속 |
1Department of Chemistry, 2Pukyong National Univ., 3Busan 48513, 4South Korea, 5Shanghai Public Health Clinical Center Fudan Univ. |
| 키워드 |
cell imaging |
| E-Mail |
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