| 학회 |
한국화학공학회 |
| 학술대회 |
2014년 가을 (10/22 ~ 10/24, 대전 DCC) |
| 권호 |
20권 2호, p.1943 |
| 발표분야 |
재료 |
| 제목 |
Mesoporous silica-coated luminescent Eu3+ doped GdVO4 nanoparticles for multimodal imaging and drug delivery |
| 초록 |
We describe a simple route for synthesizing mesoporous silica-coated luminescent europium-doped gadolinium vanadate (GdVO4:Eu3+@mSiO2) nanoparticles. Their biomedical applications as a potential imaging nanoprobe for both fluorescence imaging and magnetic resonance imaging (MRI) and as a simultaneous anti-cancer drug delivery vehicle are also discussed. Eu3+ doped GdVO4 nanoparticles exhibit strong red photoluminescence and the Gd3+ in GdVO4 can be used as a T1 contrast agent for MRI. The mesoporous silica layer on the nanoparticles enables the simultaneous capabilities of T1-weighted MR contrast enhancement and sustained intracellular drug delivery. GdVO4:Eu3+@mSiO2 nanoparticles can provide new opportunities in cancer treatment as a new type of theragnostic (imaging and treatment) agents. |
| 저자 |
이민영, 유태경
|
| 소속 |
경희대 |
| 키워드 |
Europium-doped gadolinium vanadate; Mesoporous silica; Photoluminescence; MRI contrast agent; Drug delivery
|
| E-Mail |
|
| 원문파일 |
초록 보기 |
