| 초록 |
N-Heterocyclic carbenes (NHCs) as a novel class of ligands have appeared particularly relevant for the stabilization and functionalization of various materials surface. Using its physiochemical stability of the NHCs, we synthesized novel NHCs derivatives connecting the functional group as amine, acid, and azide at the end of the molecule, which were able to stably link with bio-receptors as well as improve sensor performance and reproducibility. Synthesized NHCs including functional group was powerfully bonded with nanomaterials such as gold nanoparticle and graphene. The NHCs-nanohybrid were then purified and characterized by XPS, IR, TEM, and spectroscopic techniques. NHC-conjugated biosensors showed high-performance sensing properties toward infectious disease. |
