| 초록 |
Nanoparticles have shown great promise for the diagnosis and therapy of major diseases including cancer, cardiovascular, and infectious diseases. Use of microfluidics for synthesis of these nanoparticles has been of great interest due to controllability and reproducibility in their physicochemical properties. However, productivity of microfluidic systems is lower than that of batch reactors due to low flowrates, making it challenging to produce large quantities of nanoparticles required for in vivo or clinical studies. In this work, we developed a novel coaxial turbulent jet mixer capable of synthesizing various types of functional nanoparticles with extremely high production rates suitable for series of in vivo studies and clinical trials, while maintaining the controllability and reproducibility of conventional microfluidic systems. |
