| 초록 |
In this study, we introduced biomolecules such as biotin–streptavidin, ssDNA (Aptamer), Poly-L-lysine, Hyaluronic acid (PLL/HA) on cell surface to produce e-PBMCs (engineered Peripheral blood mononuclear cells). Characterization, preparation, detection ability, morphology, loading efficiency of engineered live immune cells as cell-based platform were evaluated. This cell-based platform is expected to be useful for studying the homing mechanism of immune cells, the role of immune response intermediates, and intercellular communication. |
