| 학회 | 한국재료학회 |
| 학술대회 | 2012년 봄 (05/17 ~ 05/18, 무주덕유산리조트) |
| 권호 | 18권 1호 |
| 발표분야 | B. 나노재료(Nanomaterials) |
| 제목 | Magnetite Nanoparticles in Hybrid Aerogel and PEG encapsulated of Magnetite Nanoparticles for the Hyperthermia Application |
| 초록 | Magnetite nanoparticles have received intensive attractions because of their applications as magnetic carriers in drug targeting and hyperthermia in tumor treatment. However, magnetite nanoparticles with 10 nm in diameter easily aggregate themselves to form large secondary particles. To disperse magnetite nanoparticles, this research paper suggests the infiltration of magnetite nanoparticles into hybrid silica aerogels. The PEG encapsulate of magnetite is to disperse magnetite up in PBS solution. The well-dispersion of magnetite is necessary for target the tumor cells and hyperthermia treatment. Methyltriethoxysilicate (MTEOS) based hybrid silica aerogels were synthesized by a supercritical drying method. To incorporate magnetite nanoparticles into the hybrid silica aerogels, we immersed it into magnetite precursor solution. The surfaces of magnetite nanoparticles were modified by PEG(polyethylene glycol). The infiltration and PEG coating of magnetite nanoparticles were identified by XRD, FT-IR and TEM. Vibrating Sample Magnetometer analysis showed that the composite of the magnetite and hybrid silica aerogel is superparamagnetic. The temperature behaviors of the magnetite composite and the surface coated magnetite nanoparticles were discussed in the context of the change of magnetite particles with PBS for Hyperthermia application. |
| 저자 | Eun-hee1, LEE2, Chang-yeoul1, KIM2, Yong-ho, CHOA |
| 소속 | 1KICET, 2Hanyang Univ. |
| 키워드 | Magnetite nanoparticles; Aerogel; Hyperthermia; surface modification |
