화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2013년 봄 (04/11 ~ 04/12, 대전컨벤션센터)
권호 38권 1호
발표분야 기능성 고분자
제목 AAO membrane reactor with the gating system
초록 The control of release system is highly needed for sophisticated drug delivery. Introducing the stimuli-responsive polymer to the release system can be for better controlled release. Here we propose the dual stimuli-responsive controlled-release system by the AAO (anodized aluminum oxide) membranes with layered surface functionalities inside the pore. Surface modification technique using stimuli-responsive polymers is carried out on the pore surfaces of the AAO, then the interior of the pore is chemically modified in layers. Upper and lower pores with different stimuli-responsive functionalities act as two gates which respond to the different stimuli. The wall of the AAO is decorated with thermo-responsive poly(N-isopropylacrylamide) and pH-responsive poly(acrylic acid) through ATRP. This system is expected to have superior storage capacity and timely release of the drugs due to the environmentally responsive properties.
저자 이봄이, 전금혜, 현승, 김진곤
소속 POSTECH
키워드 AAO; stimuli-responsive polymer; controlled release
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