| 학회 |
한국고분자학회 |
| 학술대회 |
2011년 가을 (10/06 ~ 10/07, 김대중 컨벤션센터) |
| 권호 |
36권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Micropatternednanofiber scaffolds for cell and protein microarrays |
| 초록 |
We fabricated micropatterned polymeric nanofiber scaffolds that were capable of simultaneously generating cellular micropatterns within a biomimetic environment microdomains. To achieve this, we designed nanofiber scaffolds with both vertical and lateral microdomains. Vertically heterogeneous structures that were responsible for multi-functionality were realized by preparing double-layered nanofiber scaffolds consisting of an antibody-immobilized bottom layer of nanofibers and an upper layer of bare PS nanofibers by a two-step sequential electrospinning process. Photopatterning of PEG hydrogel on electrospun nanofibers produced heterogeneous micropatterned nanofiber scaffolds made of hydrogel microwells filled with a nanofibrous region, which is capable of generating cell and protein micropatterns due to the different interactions that cells and proteins have with PEG hydrogels and nanofibers. |
| 저자 |
고원건 |
| 소속 |
연세대 |
| 키워드 |
micropattern; nanofiber scaffolds; cell patterning
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| E-Mail |
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