| 학회 |
한국공업화학회 |
| 학술대회 |
2016년 가을 (10/26 ~ 10/28, 제주국제컨벤션센터(ICCJEJU)) |
| 권호 |
20권 2호 |
| 발표분야 |
(생물공학) 단백질공학의 최신 동향 |
| 제목 |
Peptoid-based materials and their applications in biomimetic research |
| 초록 |
Peptoids are a unique class of peptidomimetics based on oligo-N-substituted glycine scaffolding. As a bioinspired material, the properties of peptoids lie in-between natural biopolymers and non-natural synthetic polymers. Peptoids are a synthetic material but it has key features such as programmability and sequence specificity that are unique in biological molecules. The structural similarity to polypeptides has been responsible for the impressive diversity of biological activity observed for peptoids; however, non-natural N-substituents render them higher stability than that of natural counterpart (i.e., protease-stable). Given the unique structural properties, the potential applications of peptoid are widely open in various fields including biomedicine and material sciences. In this presentation I will present efforts to expand the boundary of the peptoid-based materials including peptoid based bioactive agents and peptoid scaffolds for multivalent display. |
| 저자 |
서지원 |
| 소속 |
Gwangju Institute of Science and Technology |
| 키워드 |
peptoid; cell-penetrating; anticancer; porphyrin; biomimetic
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| E-Mail |
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