| 학회 | 한국화학공학회 |
| 학술대회 | 2006년 봄 (04/20 ~ 04/21, 대구 인터불고 호텔) |
| 권호 | 12권 1호, p.899 |
| 발표분야 | 재료 |
| 제목 | Surface oxidation effect for protein patterning on the glass |
| 초록 | The protein patterning is crucial technique in the bio-technology of micro-scale, such as diagnostic system, bio-sensor and high throughput screening. The cost for bio-device and analysis is cut down by reducing amount used of sample. Moreover, proteins can be immobilized on the only desired location through the various patterning techniques. However, non-specific binding and sensitivity are recognized as challenges in the protein patterning technique. It is demonstrated that the O2 plasma oxidation is the superior technique for the protein immobilization according to comparison with various oxidation techniques in this work. Self assembled monolayer is formed with 3-aminopropyltriethoxysilane (3-APTES) on the glass surface oxidized. 3-APTES immobilizes proteins at the ends of the molecules. Therefore, quality of 3-APTES self assembled monolayer is determined according to quality of oxidation. A various techniques of surface oxidation were compared to determine the most appropriate technique of all. Thereby the O2 plasma oxidation turns out the superior technique in the efficiency and economical feasibility through the analysis of fluorescent microscope. |
| 저자 | 유충한, 채희엽 |
| 소속 | 성균관대 |
| 키워드 | oxidation; surface modification; plasma |
| 원문파일 | 초록 보기 |
