| 학회 |
한국고분자학회 |
| 학술대회 |
2013년 가을 (10/11 ~ 10/12, 창원컨벤션센터) |
| 권호 |
38권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Enhanced Durability of the polymer coating layer onto cobalt-chromium substrate by nanocoupling for drug-eluting stents |
| 초록 |
The commercially available drug-eluting stents still suffer from polymer coating defects (cracking or delamination) that accompany the balloon expansion and it might be a source of thrombosis. The main purpose of this study is to improve the durability of the coated layer onto cobalt-chromium (Co-Cr) alloy through surface polymer grafting. We established a major three-step process for the surface modification. The first step includes initiator grafting for atom transfer radical polymerization (ATRP). The second step includes surface-initiated ATRP of 2-hydroxyethyl methacrylate (HEMA) as a hydroxyl group containing compound. The third step includes surface-initiated ring opening polymerization (ROP) of L-lactde. The initiator immobilization and the polymer grafting were successfully confirmed by ATR-FTIR, static water contact angle, SEM, and XPS. The topography as well as the roughness of the surface was evaluated by AFM. |
| 저자 |
타렉, 정윤기, 한동근
|
| 소속 |
한국과학기술(연) |
| 키워드 |
drug-eluting stent; durability; polymer grafting;
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| E-Mail |
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