| 초록 |
The three major components of tissue engineering include cells, scaffolds, and bioactive agents. From an engineering perspective, optimizing scaffold composition and structural composition can be the most challenging task. In order for the scaffold to perform the desired functions, biocompatibility, porosity, and hydrophilicity of the scaffolds must be optimized. In this study, a composite bone tissue scaffold capable of promoting the proliferation and differentiation of osteoblasts was prepared by combining polymer and ceramic microparticles. For the applied polymer, a blend of synthetic and natural polymers was used, and an analysis was performed on changes in cellular response depending on the mixing ratio of the polymer and ceramic particulates. The geometry, swelling, hydrophilicity, porosity, and chemical composition of the composite scaffold were characterized by using analytical instruments such as SEM, FTIR, and EDX. |
