| 학회 |
한국공업화학회 |
| 학술대회 |
2009년 가을 (10/15 ~ 10/16, 서울산업대학교 내 서울테크노파크) |
| 권호 |
13권 2호 |
| 발표분야 |
석유화학윤활유(포스터) |
| 제목 |
Graphene oxide-based immune-biosensor for pathogen detection |
| 초록 |
In this study, we demonstrated a graphene oxide (GO)-based immune-biosensor system for pathogen detection using fluorescence quenching effect between GO and gold nanoparticles. The fluorescent GO sheets was deposited on an amino-modified glass surface by electrostatic force, and the carboxylate functional group on the GO surface was used to covalently conjugate Rotavirus-antibodies to be linked on the surface. The target pathogen, Rotavirus, was then incubated and bound by a specific antigen-antibody interaction. Finally, an engineered gold nanoparticle-labeled antibody probe was attached to the captured target cell which complexes enable gold nanoparticles to be close to the GO surface, thereby resulting in the quenching of GO fluorescence signal to identify the pathogen. |
| 저자 |
정재환1, Liu Fei2, 서태석3
|
| 소속 |
1Department of Chemical and Biomolecular Engineering, 2KAIST, 3Daejeon |
| 키워드 |
graphene oxide; immune-biosensor; quenching effect; pathogen detection
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| E-Mail |
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