| 학회 |
한국화학공학회 |
| 학술대회 |
2011년 가을 (10/26 ~ 10/28, 송도컨벤시아) |
| 권호 |
17권 2호, p.1931 |
| 발표분야 |
재료 |
| 제목 |
The Characteristic Study of L-ascobic acid intercalated Bentoniteusing active ingredient carrier |
| 초록 |
One class of drug delivery vehicles that has received more attention in recent years is layered materials, which can accommodate therapeutic compounds between their layers and form a variety of intercalated compounds. Many studies have been reported on montmorillonite-drug hybrids for controlled drug delivery and about release behavior of MMT to be concluded that both the adsorption and desorption of the small organic molecules differ from those of the larger molecules. L-ascorbic acid (LAA; i.e., vitamin C, a watersoluble vitamin) contains a variety of biological, pharmaceutical and dermatological functions; for example, it can promote collagen biosynthesis, provide photoprotection, scavenge free radical, cause melanin reduction and enhances the immunity (e.g., anti-viral effect). Herein, we introduced a new method with practical value of intercalating and stabilizing vitamin C within an inorganic layered material MMT. Meanwhile, toxicity assessment also pointed out the margin of safety and toxicity rankings for feasibility of LAA-MMT composites in practical applications. |
| 저자 |
김명훈1, 장석흥2, 김동명3, 박종을4, 송윤구2
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| 소속 |
1캠브리지대, 2연세대, 3한국콜마(주) 피부과학(연), 4(주)엔탑머트리얼 기술(연) |
| 키워드 |
L-ascobic acid; Bentonite; Montmorillonite; Drug delivery; Intercalate
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| E-Mail |
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| 원문파일 |
초록 보기 |
