| 학회 |
한국공업화학회 |
| 학술대회 |
2018년 가을 (10/31 ~ 11/02, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 |
22권 2호 |
| 발표분야 |
생체재료_포스터 |
| 제목 |
Preparation and Characterization of 3D Porous PLCL Support Reinforced with Alendronate for the Acceleration of Bone Tissue Regeneration |
| 초록 |
As the elderly population increases, the number of patients suffering from bone/cartilage diseases is rapidly growing. As a result, demands on bone substitutes with a 3D porous support are increasing. In this study, we prepared a highly biocompatible and 3D porous support using polyl(actide acid-co-caprolactone) (PLCL). PLCL is known to be biodegradable, biocompatible, and elastic. In order to improve the biofunctionality of the support, alendronate was incorporated in the scaffold. PLCL was synthesized by copolymerization of lactide acid and caprolacton monomers. The physicochemical properties of the prepared scaffolds were characterized using SEM, EDX, FT-IR and HPLC. Responses of osteoblast to the scaffolds were also analyzed. |
| 저자 |
박진우, 강소연, 김민지, 박중섭, 이세진, 임은비, 이우걸
|
| 소속 |
단국대 |
| 키워드 |
PLCL; alendronate; scaffold; biocompatibility; mechanical properties
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| E-Mail |
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