| 학회 |
한국화학공학회 |
| 학술대회 |
2009년 가을 (10/22 ~ 10/23, 일산 KINTEX) |
| 권호 |
15권 2호, p.1483 |
| 발표분야 |
분리기술 |
| 제목 |
Extraction of Liquiritin and Glycyrrhizic Acid from Licorice by using Solid-Phase Extraction with Ionic Liquid-based Silica |
| 초록 |
New ionic liquid-based silica sorbent was synthesized by using commercial silica and ionic liquid. The ionic liquid-based particles obtained were used successfully as a special sorbent in a solid-phase extraction process to separate the liquiritin and glycyrrhizic acid from licorice. Different washing and elution solvents, such as water, methanol/water (v/v) and methanol were evaluated. A comparison of the ionic liquid-based silica cartridge and traditional C18 cartridges showed that higher selectivity using ionic liquid-based silica sorbent. Quantitative analysis was carried out by high-performance liquid chromatography using a C18 column with good linearity obtained from 5×10-4 to 0.2 mg/mL (r2＞0.99) with the relative standard deviations ＜1.0%. The target compounds in commercial herbal medicines containing licorice were determined, and the bound rates between the target compounds and protein were obtained by this sorbent. |
| 저자 |
이광진1, 노경호2, 전명래2
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| 소속 |
1(재)충북테크노파크, 2인하대 |
| 키워드 |
Ionic liquid-based silica; liquiritin; glycyrrhizic acid; licorice; solid-phase extraction
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| E-Mail |
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| 원문파일 |
초록 보기 |
