| 학회 |
한국고분자학회 |
| 학술대회 |
2010년 가을 (10/07 ~ 10/08, 대구 EXCO) |
| 권호 |
35권 2호 |
| 발표분야 |
고분자 합성 |
| 제목 |
Polyphosphazenes for Dendrimers and Polymeric Micelles |
| 초록 |
Three novel polyphosphazene-functionalized diaminobutane poly(propyleneimine) dendrimers have been prepared and investigated for their properties as prospective hydrophobic drug delivery systems. The introduction of amphiphilic phosphazene groups at the external surface of the dendrimers affects the solubilization and guest release properties compared to the behavior of the parent dendrimers. It has been established that these novel dendrimeric compounds exhibit useful protective and targeting properties. In addition, hydrophobic block copolymers with adamantyl-polyphosphazene and polystyrene blocks were synthesized via the controlled cationic living polymerization of a phosphoranimine at ambient temperature. β-Cyclodextrins (β-CDs) were then complexed with the adamantyl side groups in aqueous media to generate amphiphilic block copolymers. These underwent micelle formation in an aqueous environment. Micellar behavior of these complexes will be discussed in this presentation. |
| 저자 |
조성윤 |
| 소속 |
한국화학(연) |
| 키워드 |
polyphosphazene; denderimer; micelle
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| E-Mail |
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