| 학회 |
한국공업화학회 |
| 학술대회 |
2016년 봄 (05/02 ~ 05/04, 여수 엑스포 컨벤션) |
| 권호 |
20권 1호 |
| 발표분야 |
생체재료_포스터 |
| 제목 |
Scale-up synthesis for Surface-Enhanced Raman Scattering (SERS) tagging nanoparticles with high reproducibility and stability |
| 초록 |
Surface enhanced Raman Scattering (SERS) based optical nanoprobes (SERS nanoprobes) are widely used for bio-applications with high sensitivity and multiplexing capabilities. Among of them, novel metal assembled nanostructure using silica supporting materials is exhibits a strong and homogenous SERS signal due to ensemble average effect and high reproducibility in preparation. From the perspective of practical application, the facile techniques for large scale synthesis with high reproducibility and long-term stability are required. In this paper, we have proposed the scale-up synthesizing method of SERS tagging nanoparticles (SERS dots) to be fabricated up to ca. 60 mg scale. The high sensitivity and long-term stability were demonstrated by single particle detection and storage in buffer solution and deionized water for 300 hours. These features allow the SERS Dots to be utilized in practical application as a targeting agent. |
| 저자 |
김형모1, 함은일1, 김재희2, 경 산2, Pham Xuan-Hung1, 이윤식2, 전봉현1
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| 소속 |
1건국대, 2서울대 |
| 키워드 |
Scale-up; SERS nanoprobe; silica nanoparticles
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| E-Mail |
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