초록 |
Safflower seed extract shows an excellent effect, such as to increase the bone density of osteoporotic bone. In this study, we observed the effect on the proliferation, ALP(Alkaline Phosphatase) and differentiation of osteoblast using the MG-63 cell in vitro, depending on the concentration of the safflower seed extract. And study the bone cement with Hydroxyapatite and Chitosan applied to the 3D. The compressive strength is measuring and observe the form of the crystallization and the crystallization time in the process. Finally, we investigated the effect by the addition of safflower seed extract prepared in the bone cement on the in vitro. |