| 초록 |
Electrospinning is a fabrication process that uses an electric field to control the deposition of polymer fibers onto a target substrate. This electrospinning processing strategy can be used to fabricate fibrous polymer mats composed of fiber diameters ranging from several microns down to 500 nm or less. In this study, An electrospinning method was used to gelatin/poly(L-lactide-co-ε-caprolactone)(PLCL) nanofiber non wovens for cell culture of normal rat fibroblast. The electrospinning of regenerated gelatin/PLCL was performed with 2,2,2-trifluoroethanol as a spinning solvent. To assay the cell behavior onto the electrospun gelatin/PLCL nanofibers, cell attachment and spreading of normal rat fibroblast seeded on the gelatin/PLCL nanofibers and interaction between cells and gelatin/PLCL nanofibers were studied. The structural, material, and biological properties of electrospinning gelatin/PLCL suggest that this biomaterial may represent a nearly ideal skin tissue engineeing scaffold. |
