초록 |
The sterilization of medical devices is one of the most critical steps in the operation of medical clinics and hospitals. This study investigated the effects of ClO2 concentration, exposure time, temperature, and humidity on sterilization efficiency, along with modeling and optimization. The rate of ClO2 generation and decay under different sterilization conditions was evaluated. A sterilization map was established as a function of ClO2 concentration and exposure time being classified into three regions, such as sterilization, transition, and non-sterilization. Elevated temperature enhanced sterilization and its effect was incorporated into the rate constant. The ClO2 generation/decay equations fit its gas phase concentration well when its production was discontinued, but not with continuous generation. Further studies on ClO2 kinetics as well as the effect of electric current are needed. |