| 학회 |
한국고분자학회 |
| 학술대회 |
2007년 가을 (10/11 ~ 10/12, 일산킨텍스) |
| 권호 |
32권 2호 |
| 발표분야 |
의료용 고분자 |
| 제목 |
pH-sensitive, Hydroxypropylmethacrylate(HPMA)-based Hydrogels:Controlling of swelling/deswelling and drug release behaviors |
| 초록 |
A pH-responsive hydrogels as well as HPMA(2-Hydroxypropyl methacrylate)and DMA(N,N-dimethylaminoethyl methacrylate) is essenstial for controlled drug release. HPMA-based hydrogels are one of the most widely used. The goal in this study is to manipulate the swelling/deswelling and drug release behaviors of HPMA-based hydrogels by controlling the physical and chemical properties of the copolymer network. And,the other goal in this study is to show the swelling/deswelling and transparency by changing backbone , sidechain and crosslinker. Different hydrogels were prepared by free radical copolymerization of HPMA and DMA(N,N-dimethylethylaminoetyacrylate). Swelling characteristics and drug release profiles were investigated as a function of pH values. |
| 저자 |
최순모1, 조용우2, 한성수1, 류원석1, 조준우1
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| 소속 |
1영남대, 2한양대 |
| 키워드 |
Hydrogel; pH-sensitive; Drug Delivery; HPMA
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| E-Mail |
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